The diagnosis of skin necrosis is complex, since this It is not specific to any particular pathology.. Its causes are multiple and therefore, to establish the diagnosis, it is necessary to carefully examine the clinical context of each patient.
The pathological history of the person, as well as associated diseases and other symptoms, together with the data provided by the laboratory are the variables to consider. The analysis of all these aspects is what allows you to reach a diagnosis. concrete, As indicated by the scientific literature.
Anyway, The truth is that skin necrosis is a very serious disease. Once it occurs and develops, it becomes irreversible. Therefore, it is essential to act quickly to establish the cause and administer the appropriate treatment.
What is skin necrosis?
Skin necrosis is defined as ‘the death of a group of cells or tissues for pathological reasons’. The process obeys a noxious agent which causes a lesion serious enough to make it impossible to cure.
Typically, skin necrosis presents as a purple, blue or black discoloration of the skin. There is loss of sensation in the area, which is sometimes preceded by intense pain. There is also a smelly drain.
Typically, skin necrosis is covered by a it is expensive. It is a kind of plate, black in color, which has defined limits. Its configuration is hard and is completely adherent to the lesion.
This process can result in tissue death over a large area of ​​the skin, due to lack of blood supply. If this is accompanied by an infection bacterial and decomposition, then we speak gangrene.
Processes that occur with necrosis due to infection
All the factors that give rise to skin necrosis are pathologies that occur in parallel. In the case of skin necrosis due to infection, the associated processes are usually:
- ecthyma. Bacterial infection that gives rise to ulcers and scabs.
- Necrotizing fasciitis. It generates rapid necrosis of the subcutaneous fat and fascia, which produces a foul-smelling watery liquid.
- gas gangrene. Muscle infection that has a very rapid course and can lead to death.
- Acute meningococcemia. Causes an acute petechial rash, which may be followed by bruising and ischemic necrosis. Sometimes it generates hemorrhagic bullous lesions.
Processes that occur with necrosis due to vascular occlusion
As a consequence of wound infection, gangrene can occur among one of its complications.
In the case of skin necrosis due to vascular occlusion, the following concomitant processes are normal:
- Antiphospholipid syndrome. It is an immune disease in which the body mistakenly attacks proteins in the blood.
- cryoglobulinemia. It is a rare disease, almost always associated with hepatitis C. The affected person has proteins in their blood that thicken at low temperatures.
- cholesterol embolism disease. It is a rare disease that occurs mainly in men over the age of 60 with generalized arteriosclerosis. In it there is an embolization of microcrystals of cholesterol.
- calciphylaxis. It is a rare and potentially fatal syndrome. It results from calcification of the vessels and is characterized by progressive and painful ulcerations.
- Necrotizing vasculitis. It corresponds to a group of disorders that cause inflammation of the blood vessel walls.
- Hemostasis disorders. It comprises a group of disorders in which the normal activation of platelets is disturbed, affecting the walls of blood vessels.
As we have seen, there is a whole range of processes associated with skin necrosis. This is what makes his diagnosis so complex, even today. However, science continues to study ways to facilitate diagnosis.
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